Ingredient Technology · 04
SquaActive™
99%
HPLC Purity
Powered by ArcoPure™
Botanical name: Amaranthus speciesCAS: 111-02-4Dose: Application-dependent — see technical dossier
An Amaranthus-derived squalene standardized to 99% HPLC purity — a plant-based alternative to shark- and olive-derived squalane, serving both cosmetic emollient applications and pharmaceutical adjuvant-precursor applications.
// Key advantages
99% HPLC Purity
Plant-Based Alternative
Patent-Pending Technology
Dual Cosmetic / Pharma Grade
// Specification
| Botanical name | Amaranthus species |
| CAS | 111-02-4 |
| Standardization | 99% HPLC Purity |
| Dose | Application-dependent — see technical dossier |
| Appearance | Light yellow |
| Solubility | Soluble in non-polar solvents (oils, hexane, chloroform, ether); insoluble in water |
| Shelf life | 2 years |
| Country of origin | India |
| Raw material source | Edible seeds of Amaranthus |
Full certificate of analysis and technical dossier available on request.
// Mechanism
Isolated and purified from Amaranthus oil to 99% HPLC purity via ArcoPure™, positioned as an Amaranthus-based alternative to MF59-type squalene adjuvant components — a component supplier claim, not a vaccine claim.
Read the compound-level science →// Benefits
- Emollient, anti-aging skin support (cosmetic use)
- Non-comedogenic, clean-beauty positioning
- Vaccine-adjuvant precursor component (pharmaceutical use)
- Drug delivery and wound-care applications
Squalene's role as a vaccine-adjuvant component is supported by 5 published reviews and studies on squalene-based (MF59-type) adjuvants below — these describe squalene as a compound class; SquaActive is a component supplier ingredient, not a tested vaccine formulation in its own right.
Applications: Cosmeceuticals · Pharmaceuticals
// Key research
- "MF59: a safe and potent vaccine adjuvant" — reviews the mechanism, safety profile and vaccine-response potential of the squalene-based MF59 adjuvant.Brito & Brodin — Current Drug Targets ↗
- Squalene-based oil-in-water emulsion (MF59) improved antigen-specific T-cell-mediated immune responses in mice.Leroux-Roels & Leroux-Roels — Vaccine ↗
- Advances in squalene-based adjuvants and emulsions — efficacy, safety and regulatory considerations for vaccine use.Singh, Kumar & Gupta — Expert Review of Vaccines ↗
- Historical development, current use and safety/immunogenic properties of squalene as a vaccine adjuvant in humans.Del Giudice & Rappuoli — Pharmaceuticals ↗
- Role of squalene in enhancing immunogenicity of pandemic influenza vaccines, including mechanism of action.O'Hagan & Wack — Immunology and Cell Biology ↗
Citations refer to published literature on these compounds generally, not to clinical trials of Arceli’s specific extract unless otherwise noted. Full dossier available on request.
// Frequently asked
What is SquaActive™ standardized to?
SquaActive™ is standardized to 99% HPLC Purity, verified on every batch using validated analytical methods and powered by Arceli's ArcoPure™ purification platform.
Is SquaActive™ patent-pending?
Yes — SquaActive™ is produced using Arceli's ArcoPure™ technology, covered by a provisional patent application (public record).
What industries use SquaActive™?
SquaActive™ is formulated for Cosmeceuticals, Pharmaceuticals.
What is the typical dose for SquaActive™?
Application-dependent — see technical dossier. Application-specific dosing should be confirmed against the full technical dossier.
What botanical source is SquaActive™ derived from?
SquaActive™ is derived from Amaranthus species (CAS 111-02-4).
What is the shelf life of SquaActive™?
2 years when stored sealed in the original container at room temperature, sheltered from light and moisture.
Is SquaActive™ water-soluble?
Soluble in non-polar solvents (oils, hexane, chloroform, ether); insoluble in water
What does SquaActive™ look like?
Light yellow. Natural batch-to-batch variation in raw material can cause minor color variation without affecting quality or efficacy.
Arceli Lifescience